“Worlds of Hurt” – Tough Guy (earned on 2010-01-09 19:17:08)
Rescued the Little Sister in “Worlds of Hurt” using only plasmids, tonics, the wrench, and the research camera, on Medium or higher difficulty
EP1: The Math Master (earned on 2010-07-09 19:16:17)
This trophy is awarded when the player earns a gold medal in the most math-intensive puzzle of the episode during the Story Mode
EP1: The Fastest Answer (earned on 2010-07-09 19:16:17)
This trophy is awarded the first time a player solves a puzzle in half of the gold award time during the Story Mode
Stay on Target (earned on 2011-07-19 04:08:24)
Stay locked onto an opponent with a Missile or a Leech Beam for 30 seconds in a single player Eliminator event.
Fashion Sense (earned on 2011-06-11 21:44:19)
Choose a costume for your sackperson with at least one item on your head, at least one item on your body, and a material